Bicor is used alone or together with other medicines to treat high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled.

This medicine is a beta-blocker. It works by affecting the response to nerve impulses in certain parts of the body, like the heart. As a result, the heart beats slower and decreases the blood pressure. When the blood pressure is lowered, the amount of blood and oxygen is increased to the heart.

This medicine is available only with your doctor's prescription.

This product is available in the following dosage forms:

• Tablet

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Reciprocal activation of muscles on the target side and co-contraction of muscles on the contralateral side were seen when standing in asymmetrical stance and being subjected to external perturbations. However, the probing depth could be further increased by increasing the thickness of the embedded tissue sections. Association of auto-immunity has been reported to be almost threefold higher in patients with celiac disease.

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Sensitivity and accuracy of measurement with various detector arrangements Selective PDE5 inhibitors have shown potential in treating kidney fibrosis in patients with chronic kidney disease (CKD), via their downstream signaling, and these inhibitors also have known activity as antithrombotic and anticancer agents. ABC-SysBio combines three algorithms: ABC rejection sampler, ABC SMC for parameter inference and ABC SMC for model selection.

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During every exchange cycle, the seed size and position within the nanorod were preserved, as evident by excitonic features, Z-contrast imaging, and elemental line scans. An approach using auto-correlated relaxation rates acquired at five magnetic fields, applicable to anisotropically moving molecules, was used in the latter case. The objective of the present study was to compare P792, a new rapid clearance blood pool agent characterized by negligible interstitial diffusion but unrestricted glomerular filtration, with Gd-DOTA in both qualitative and quantitative aspects of renal functional magnetic resonance imaging. Phlebographic localization of supra-renal adenomas in primary aldosteronism T-cell receptors modify neuronal function in the central nervous system.

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The Interplay of Symmetry and Scattering Phase in Second Harmonic Generation from Gold Nanoantennas. To understand the patterns of this convergent plastome reduction syndrome in heterotrophic plants, we studied 12 closely related orchids of three different lifeforms from the tribe Neottieae (Orchidaceae). We validate that the evolved controllers display key properties of swarm intelligence-based control, namely scalability, flexibility, and robustness on the real swarm. The Hartmann-Shack instrument is an outgoing reflective aberrometer that uses a laser light source.

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The topic of investigating how mindfulness meditation training can have antidepressant effects via plastic changes in both resting state and meditation state brain activity is important in the rapidly emerging field of neuroplasticity. In December 2008, after receiving preoperative chemotherapy consisting of q3w 4 cycles of EC (E: 90 mg/m2, C: 600 mg/m2) and 12 cycles of weekly paclitaxel (80 mg/m2), the patient underwent modified radical mastectomy with axillary lymph node dissection for right breast cancer. The O-specific polysaccharide from the marine bacterium Pseudoalteromonas agarivorans KMM 255(T).

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Furthermore, when the SOC strength increases, the dipole oscillations of the two pseudospin components undergo a transition from in-phase to out-of-phase oscillations. Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominant disorder associated mainly with tumors of multiple endocrine organs. The clinical characteristics of newly diagnosed acute myeloid leukemia patients with NPM1 mutation Paramunity inducers are based on attenuated and inactivated poxviruses (avipox virus and parapox virus).

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Our findings raise the possibility that endogenous ghrelin has a role in physiologic insulin secretion, and that ghrelin antagonists could improve beta-cell function. However, current red GECIs are inferior to the state-of-the-art GFP-based GCaMP6 indicators for detecting and quantifying neural activity. Patterned species occurring at higher altitudes had larger UV-absorbing petal areas, corresponding with low temperature and high UV exposure.

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To systematically study the formation of crumples in graphene, we use a simple molecular dynamics model, and perform a series of simulations to characterize the finite number of deformation regimes of graphene on substrate after compression. We demonstrate that dewetting forces between an oil phase and solid colloidal substrates can be exploited to engineer shape-shifting particles whose geometry can be changed on demand by a chemical or optical signal. On the burn surface, microorganisms exist within a complex structure termed a biofilm, which enhances bacterial resistance to antimicrobial agents significantly. Upon attachment to the substrate, the cells take up the plasmid DNA and express the particular protein encoded at each location.

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Public drinking water treated with chemical disinfectants contains a complex mixture of disinfection by-products (DBPs) for which the relative toxicity of the mixtures needs to be characterized to accurately assess risk. Galeterone/VNPT55 decreased fAR/AR-V7 mRNA levels and implicates Mdm2/CHIP enhanced ubiquitination of posttranslational modified receptors, targeting them for proteasomal degradation.

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The present data suggest that the cortical representation of auditory space is adjusted to coincide with spatially disparate tactile input. Persistence to treatment by type of inhaler device in patients with asthma and chronic obstructive pulmonary disease Effect of dehydroepiandrosterone on aggrecanase expression in articular cartilage in a rabbit model of osteoarthritis.

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Our results suggest that patients with refractory epilepsy with high serum levels of the antiepileptic drugs studied are at higher risk of accelerated forgetting. To evaluate radiation dose reduction in patients undergoing transarterial chemoembolization with the use of a new image acquisition and processing platform. Not communicating uncertainty blurs the contrast between evidence-based recommendations and those without evidence.

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The native abdomen in a standing position presented air fluid levels with moderate distension of the accompanying bowel loops. Hypoxia regulates BMP4 expression in the murine spleen during the recovery from acute anemia. Chronic pancreatitis leads to numerous inpatient readmissions, but surgical intervention only occurs in a minority of cases. Treatment with commonly prescribed antibiotics is associated with high rates of recurrence after initial cure.

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Accessible health care is viewed through a public health lens by which changes in public policy and social views of disability are necessary for achieving sustainable long-term success. Recently, biliary neoplasms resembling intraductal neoplasms of the pancreas have been documented. The goal of this study was to assess the net impact of education, occupational class, income and wealth on frailty trajectories among older adults in Continental Europe.

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The sense of identity and symptoms of personality disorders - The results of a non-clinical population study. We demonstrate that DHSO cross-linked peptides display the same predictable and characteristic fragmentation pattern during collision induced dissociation as amine-reactive sulfoxide-containing MS-cleavable cross-linked peptides, thus permitting their simplified analysis and unambiguous identification by MS(n). Systemic infusion of angiotensin II exacerbates liver fibrosis in bile duct-ligated rats. The Development and Deployment of a Maintenance Operations Safety Survey. Instead, evolution is constrained by the set of available and viable phenotypes.

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The studies have shown that uncontrolled pain experienced during early life has negative and long-term side effects, such as distress, and such experiences negatively affect the development of the central nervous system. Measures to enhance job satisfaction include the reduction of workload, increase of welfare, maintaining moderate stress and balancing work-family conflict. The morphologic right ventricle (mRV) is the systemic ventricle and prone to premature failure, particularly in the presence of early TV regurgitation, atrial arrhythmias conduction defects, and prior surgical ventricular septal defect closure. We found that, although ipsilateral inputs from the AON were uniformly distributed, feedback from the contralateral AON had a strong ventral bias.

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