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Actios (Acyclovir)
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Acyclovir

Actios is an antiviral drug, a synthetic nucleoside analogue, that has inhibitory activity (interferes with viral replication) against the herpes viruses, including herpes simplex 1 and 2 (cold sores and genital herpes), varicella-zoster (shingles and chickenpox), and Epstein-Barr virus (mononucleosis). Viruses take over living cells and reproduce themselves, often at the expense of the host cell. The Actios is converted to an active form by the virus itself, and the virus then uses the active form of Actios rather than the nucleoside it normally uses to manufacture DNA, a critical component of viral replication. Incorporation of active Actios into new viral DNA stops the production of the DNA. Virally infected cells absorb more Actios than normal cells and convert more of it to the active form, which prolongs its antiviral activity. The FDA approved Actios in March 1982.

Other names for this medication:
Acyclovir, Abduce, Acic, Aciclobeta, Aciclomed, Aciclostad, Aciclovirum, Acifar, Acihexal, Aciklovir, Acitop, Acivir, Acivirex, Acivision, Acix, Actios, Activir, Acycloguanosine, Acyl, Acyrax, Acyvir, Aklovir, Antivir, Asiviral, Avir, Aviral, Avix, Avorax, Blistex, Cicloferon, Cicloviral, Clinovir, Clirbest, Clopes, Clovate, Clovir, Cusiviral, Cyclomed, Cyclovax, Cyclovex, Cyclovir, Danovir, Declovir, Epsin, Eurovir, Hascovir, Hernovir, Herperax, Herpesil, Herpesin, Herpex, Herpin, Herplex, Heviran, Immunovir, Lisovyr, Lovir, Lovire, Lovrak, Medovir, Menova, Ocuvir, Poviral, Ranvir, Remex, Rexan, Scanovir, Sitavig, Sophivir, Soviclor, Supraviran, Telviran, Uniplex, Vilerm, Viraban, Viralex, Viratac, Viratop, Virest, Virestat, Virex, Virless, Viroclear, Virolex, Viromed, Virosil, Virostatic, Virovir, Virucid, Viruderm, Virustat, Virux, Vivorax, Xiclovir, Xorox, Zevin, Ziverone, Zoral, Zorax, Zoraxin, Zovirax,

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Actios is used to decrease pain and speed the healing of sores or blisters in people who have varicella (chickenpox), herpes zoster (shingles; a rash that can occur in people who have had chickenpox in the past), and first-time or repeat outbreaks of genital herpes (a herpes virus infection that causes sores to form around the genitals and rectum from time to time). Actios is also sometimes used to prevent outbreaks of genital herpes in people who are infected with the virus. Actios is in a class of antiviral medications called synthetic nucleoside analogues. It works by stopping the spread of the herpes virus in the body. Actios will not cure genital herpes and may not stop the spread of genital herpes to other people.

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Forty-five publicly accessible, online stories posted by families who experienced TTTS were analyzed using grounded theory. Aging is usually accompanied by alterations of cognitive control functions such as conflict processing.

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However, the utility of the RR score in clinical practice has not been independently validated. Mammary tumorigenesis in C3H-A(vy)fB female mice is not due to milk-borne mammary tumor virus but to factors transmitted at conception.

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Other common human bacteria were screened for the presence of these lipids, and they were found, amongst others, in the oral pathogen Tannerella forsythia. Legacy of a Chemical Factory Site: Contaminated Groundwater Impacts Stream Macroinvertebrates. The significance of copper chelators in clinical and experimental application. Further, we compared the binding efficiency of both native and mutant pRB (E746G) with E2F-2. Top-down modulation in the infant brain: Learning-induced expectations rapidly affect the sensory cortex at 6 months.

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Environmental Pressure May Change the Composition Protein Disorder in Prokaryotes. Locating Purity within Corruption Rumors: Narratives of HPV Vaccination Refusal in a Peri-urban Community of Southern Romania. FFP at both ages significantly increased expression of four different adhesion molecules compared with LR in PECs.

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After active orthodontic treatment and prosthetic restoration, her open bite was corrected, and she had a harmonious smile line. The use of LNR may standardize the staging and guide decisions for adjuvant treatments. Clinical presentation and imaging results of patients with symptomatic gluteus medius tears.

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Obtained results demonstrated how loading procedure influenced paclitaxel crystallinity into the matrix and consequently drug diffusion and its cytoreductive potential. We validated the algorithm and demonstrated its high efficiency in constructing ML-hGRNs governing biological pathways. We tested the impact of age, sex and mating on post-infection survivorship in Tribolium castaneum flour beetles, as well as the components of baseline constitutive innate immunity and external (secreted) immune function in uninfected individuals. The possibilities and limitations of simultaneous EEG-fMRI registration--the alpha rhythm study Therefore, the combination treatment is a recommended disinfection method.

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In this study, 116 subjects performed a WM updating task that required the memorisation of short lists of words and the within-trial removal of some of these items from WM. Influence of mycoplasma infections in permanent cell cultures on the propagation of enteroviruses and the elimination of mycoplasma infections using antibiotic therapy

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Nerve growth factor and NT3 are neurotrophic factors that may protect nerves from mechanical and metabolic damage. Erythrocyte creatine as a marker of intravascular hemolysis due to left ventricular outflow tract obstruction in hypertrophic cardiomyopathy. Ironically, while such changes in Egr-1 expression clearly favor steatosis and even fibrosis development, the absence of Egr-1 expression can actually exacerbate liver injury after excessive alcohol consumption or after exposure to other hepatotoxins. However, pluripotency is generally considered to be an almost singular state, with subtle differences described between induced pluripotent stem cells (iPSCs) and embryonic stem cells (ESCs). As expected, significant differences in functional connectivity both between states (rest versus meditation) and between time points (before versus after training) were observed.

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Experimental evidence of a symbiosis between red-cockaded woodpeckers and fungi. We present a combined PET/7 T MR imaging and 16.4 T microscopic MR imaging dual-modality imaging approach enabling quantification of the amyloid load at high sensitivity and high resolution, and of regional cerebral blood flow (rCBF) in the brain of transgenic APP23 mice. Serial deletion and mutant analysis of the clusterin promoter demonstrated that insulin-stimulated transactivation is mediated via a non-canonical E-box (NCE-box) motif in the proximal upstream region. Management of prenatally diagnosed abdominal lymphatic malformations.

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A new technique of direct phonoplasty under local anaesthetic is described. Because of coil limitations, four high-field magnetic resonance examinations showed decreased diagnostic value. Successful placement was achieved in all, with significant improvement in symptoms and cholestasis.

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Pogonatherum paniceum is a highly drought- and salt-tolerant plant species that is typically used for ecological restoration and the conservation of soil and water in many countries. Percutaneous left atrial appendage closure (LAAC) is increasingly performed as an alternative to oral anticoagulation (OAC) in patients with nonvalvular atrial fibrillation (AF). The area enclosed by the time-temperature curve, DeltaQ, was then used for quantification of the lesion. The transcription factor LIM-class homeobox gene Lim1 is required for normal organogenesis, including nephrogenesis, by regulating cell movements, differentiation and growth.

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To investigate the effectiveness and safety of telerehabilitation intervention pwMS. Cytomegalovirus infections in different groups of paediatric patients. Furthermore, the cell-to-cell communication ability was also demonstrated in a number of additional pseudomonads.

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In the context of the hyper-CVAD regimen, early anthracycline intensification did not improve outcome for adults with de novo ALL or lymphoblastic lymphoma. A single iron biomarker is unlikely to best predict iron deficiency in pediatric IBD. Oral health status was measured using oral hygiene index - simplified (OHI-S), Silness and Loe Plaque index, Community Periodontal Index (CPI) and Loss of Attachment (LA) as well as decayed-missing-filled teeth (DMFT) index. To analyse the data from Demographic and Health Survey (DHS) linking HIV serological data and fertility, and to recommend new age-specific fertility rate (ASFR) ratios of HIV-positive women to HIV-negative women to be used in the WHO/UNAIDS HIV estimates. An analysis of wait times and mortality in this era as well as the pre-lung allocation score (pre-LAS) era of 2002 to 2004 was performed.

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Neuroendocrine tumors of pancreas: how can we apply the 2006 TNM proposal? Our aim was to review and discuss the recent advances in the knowledge of the RA-associated atherogenesis. Stretching the limits of knowledge attainable with live cell imaging in ARTs. Pharmacotherapy: Is there a place for leflunomide in the treatment of RA? In comparison with the conventional TiO2 ESL, the WO(x) ESL exhibited comparable light transmittance but higher electrical conductivity.

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Although immunoreactivity was present in the granular layer of the dentate gyrus, it was difficult to identity individual immunopositive cells, possibly due to the density of cells. Vascular proliferation, bare nuclei, intracytoplasmic fat vacuolation, high cellularity, and the absence of colloid were significantly associated with the parathyroid origin. Their service characteristics and the economic and societal factors of the countries of origin were classified. Rous sarcomas in mice: the chromosomal progression during early in vivo transplantation.

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Effect of Enalapril on Preventing Anthracycline-Induced Cardiomyopathy. B cell antigen receptor signaling on B-1 cells is controlled by several inhibitory receptors, including Siglec-G, which is a member of the Siglec (sialic acid-binding immunoglobulin-like lectin) family and inhibits B cell signaling.

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Post-mortem levels and tissue distribution of codeine, codeine-6-glucuronide, norcodeine, morphine and morphine glucuronides in a series of codeine-related deaths. Regulatory acceptability of the minipig in the development of pharmaceuticals, chemicals and other products. Invasive aspergillosis (IA) causes significant morbidity and mortality among immunocompromised hosts.

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More recently, a handful of studies have indicated that age may play a crucial role in the reduced neurocognitive integrity in these chronic pain patients. Initial ultrasound of the patient showed distended urinary bladder containing Foley catheter ballon with clamping of Foley catheter and particulate ascites. It has been hypothesized that the OR is generated in response to novelty such as in the case where a mismatch results between an internal neuronal template stored in working memory and incoming stimuli. Improvement of Hemoglobin with Repeated Health Checks Among Women in Bangladesh.

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A new type of hybrid atom-light interferometer is demonstrated with atomic Raman amplification processes replacing the beam splitting elements in a traditional interferometer. Post-VAS and post-FPDS showed significant improvement in patients in MAS group.

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Abdominal pregnancy is a rare form of ectopic pregnancy with very high maternal and fetal morbidity and mortality. In order to quantify the effect of increasing loads on the GRF we define the compression area, restitution area, and coefficient of restitution (COR) for GRF curves. Fitting behavioral performance with a learning function provided a measure of learning rate. The xenobiotic compounds from tobacco are metabolized by the cytochromes P-450. without) DSH, and if the association between DSH and emotion dysregulation remains significant when controlling for their shared association with risk factors for both, including borderline personality disorder (BPD), posttraumatic stress disorder (PTSD), childhood abuse, and substance use severity.

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An online method combining a Gasbench II with continuous flow isotope ratio mass spectrometry to determine the content and isotopic compositions of minor amounts of carbonate in silicate rocks. The suggested model formulations with dry extract ofbearberry of confirmed skin-bleaching effect may be the base for offering a new line of dermatological preparations applied in the treatment of melanoderma. The capsules that contained the spermatozoa were cryopreserved on polycarbonate or nylon mesh sheets using nitrogen vapor. Black adolescents are at increased risk of cardiometabolic disease but have lower fasting triglyceride, which is usually associated with decreased risk.

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CFR in both culprit and nonculprit coronary arteries decreases after AMI with contributions from both an increased baseline flow and a decreased hyperemic flow. Common issues pertaining to the hidden curriculum exist across all levels of learners, including faculty. A mixed-methods approach is used, given the scarcity of literature.

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Immune response to Propionibacterium acnes in patients with sarcoidosis--in vivo and in vitro. Concerted efforts are now needed to synthesize and integrate the burgeoning genomic data resources into a coherent universal tree of life and genome-based taxonomy. Noncanoncial signal recognition particle RNAs in a major eukaryotic phylum revealed by purification of SRP from the human pathogen Cryptococcus neoformans. Computation of conformational entropy from protein sequences using the machine-learning method--application to the study of the relationship between structural conservation and local structural stability.

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Morphologic spectrum of primary and secondary liver tumors in children The Nuclear Factor I-X (NFIX) is a member of the nuclear factor I (NFI) protein family and is deleted or mutated in a subset of patients with a peculiar overgrowth condition resembling Sotos Syndrome as well as in patients with Marshall-Smith syndrome.

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The diurnal variation of the concentration of corticosterone in plasma in experimental trypanosomiasis in mice. Phase III lots can be produced in a consistent manner with predictable immune response and acceptable safety profile similar to previously characterised phase II lots.

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Electronic records from general practices (GPs) in four east London boroughs were queried for the number of people diagnosed with MS, grouped by ethnicity, into 5-year age bands. These results indicated that Sphk1/S1P regulates the expression of IL-17A in activated microglia, inducing neuronal apoptosis in cerebral ischemia/reperfusion.

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Taken together, the results not only reveal a Bid-mediated mitochondrial pathway in HCC cells induced by CK but also suggest that CK may become a potential cytotoxic drug targeting Bid in the prevention and treatment of HCC. We present a 25 years old Nigerian who had a live related kidney transplant and later had 3 consecutive pregnancies and review the relevant literature. Cloning and characterization of equine CD89 and identification of the CD89 gene in chimpanzees and rhesus macaques.

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An equivalent contrast-enhanced (CE) MRA injection protocol was developed with controlled injection modalities (injection rate, volume, and dose) in rabbits and pigs. The differences in threshold level between the ipsilateral and contralateral ears were calculated, and the temporal pattern and dose-response relation of hearing loss were analyzed using statistical methods that take into account the correlation between two ears in the same subject and repeated, sequential measurements of each subject. To examine clinical and genetic risk factors for determining individual susceptibility of PDD in patients with Parkinson disease.

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Median time intervals (in calendar days) with interquartile range were the main outcome measure. FDG-PET is now performed in a wide variety of tumors and indications, including diagnosis, staging, re-staging and evaluation of the response to treatment. Early Biomarkers of Renal Damage in Relation to Arterial Stiffness and Inflammation in Male Coronary Artery Disease Patients. Screening of ectopic ACTH-producing tumor associated with lung neoplasms and 2 cases diagnosed by this method

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To disentangle this issue we measured adaptation of numerosity of 10 pairs of connected dots, as connecting dots makes them appear to be less numerous than unconnected dots. A New Species of Seed-harvester Ant, Pogonomyrmex hoelldobleri (Hymenoptera: Formicidae), from the Mohave and Sonoran Deserts of North America. Supratentorial primitive neuroectodermal tumours of the brain: multidirectional differentiation does not influence prognosis. Phosphoinositide 3-Kinase Gamma Contributes to torvacard 20 mg cenacolo Neuroinflammation in a Rat Model of Surgical Brain Injury. Research has demonstrated that psychosocial stressors increase smoking and risk for smoking relapse.

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Incorporation of phenylalanine-H3 into ascidian larvae developed in sea water without SO-4 ions The dioxins and PCBs contents were determined, according to EPA olmesartan amlodipine dosage and side methods, by gas chromatography ic determination coupled with high resolution mass spectrometry (HRGC-HRMS). Accelerated intellectual growth and personality development as seen in phenylketonuric subjects during medical treatment. More than half of the HFPDD children were suffering from non-psychotic delusions, and these delusions were associated with anxiety and depression. Prognostic assessments of medical therapy and vestibular testing in post-traumatic migraine-associated dizziness patients.

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Electrokinetic sample preconcentration and hydrodynamic sample injection for microchip electrophoresis using a pneumatic microvalve. The sample comprised largely Caucasian, well-educated, and partnered women, which limits generalizability of the findings. We did this trial to develop definitive melphalan renal dosing for augmentin evidence regarding the choice of initial analgesia and route of administration in participants presenting with renal colic to the emergency department. A Baseline Patient Model to Support Testing of Medical Cyber-Physical Systems. Development and Validation of Broad-Range Qualitative and Clade-Specific Quantitative Molecular Probes for Assessing Mercury Methylation in the Environment.

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Natural selection, origin and evolution of living and thinking beings Pregnant women performed a movement task that involved standing from a chair, picking up plates, and walking forward after turning to the right. Therefore, the aim of the present study was to determine if calcium-modified acidic candies have reduced fluconazole dosage for urinary tract infection erosive potential in irradiated cancer patients. The ileus decreased with conservative treatment, however, autoimmune hemolytic anemia (AIHA) was diagnosed due to worsening anemia, a positive direct Coombs test, low haptoglobin, high lactase dehydrogenase, reticulocytosis, and an increase in the erythroblastic series in a bone-marrow examination.

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