Totalip is used along with a proper diet to help lower "bad" cholesterol and fats (such as LDL, triglycerides) and raise "good" cholesterol (HDL) in the blood. It belongs to a group of drugs known as "statins. " It works by reducing the amount of cholesterol made by the liver. Lowering "bad" cholesterol and triglycerides and raising "good" cholesterol decreases the risk of heart disease and helps prevent strokes and heart attacks. In addition to eating a proper diet (such as a low-cholesterol/low-fat diet), other lifestyle changes that may help this medication work better include exercising, losing weight if overweight, and stopping smoking. Consult your doctor for more details.

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The short- and long-lasting effects induced by TT on walking performance are specifically affected by the frequency of training, possibly in relationship to learning mechanisms and fatigue. Decoding breast cancer tissue-stroma interactions using species-specific sequencing. A neuroendocrinological perspective on human hair follicle pigmentation.

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In this work we review the role played by RGS proteins in the intensity and duration of the effects of mu-opioid receptor agonists, and how they influence the delayed tolerance that develops in response to specific doses of opioids. Predictors of unsafe sex among HIV patients in Denmark: a population-based cohort study. We adapted a cell culture method previously developed for CNS neurons to establish a neuron-enriched primary culture from embryonic rat intestine which was cultured in indirect coculture with EGCs.

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Cleaning the oral cavity and eating breakfast are important to prevent oral malodor in high school students. An adequate level of physical activity needs to be integrated into daily life, and stimulation of physical activity when absent is important. Improvement in best-corrected visual acuity after three injections of bevacizumab can be predicted from optical coherence tomography measurements.

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The principle of this experiment, two-wavelength interferometry, is described, and the results of the measurement are presented and discussed. Although DLC1 expression has been studied at the transcriptional level, little is known about its regulation at the protein level. The activation energy difference between the two forms suggests that trans trielaidin radicals are more stable than cis triolein radicals. ZnO nanoparticles (NPs) are among the most commonly used metal oxide NPs in personal care products, coating and paints. Excluded boys were significantly poorer than controls on expressive measures but similar on receptive language and non-verbal IQ.

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There was no evidence of CRAB contamination in either of the units. Current therapeutic options to treat patients infected with toxin-producing bacteria are limited. The nasty neighbour in the striped mouse (Rhabdomys pumilio) steals paternity and elicits aggression. We have developed a novel technique of introducing the mesh at the distal dissection. To improve compliance to maternal referrals there is need to review the referral indications and strengthen counseling on birth preparedness and complication readiness.

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Hybridization results and differences in growth characteristics and substrate utilization differentiated strain KOD1 from T. Regional musculoskeletal pain such as back or shoulder pain are commonly reported symptoms in the community. The male lineages J-12f2.1 and T-M70 were also well represented, and both were shared with descendants of Sephardic Jews. The impression and plan of the attending surgeon were recorded before and after each in-person review. Novel Prokinetic Acotiamide Reduces Transient Lower Esophageal Sphincter Relaxation in Healthy Subjects.

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Characterization of virulence factors and clonal diversity of Enterococcus faecalis isolates from treated dental root canals. Gypsy moth pheromone-binding protein-ligand interactions: pH profiles and simulations as tools for detecting polar interactions. In this study, we show that their survival critically relies on the redundantly acting SoxC transcription factors Sox4, Sox11 and Sox12.

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Oxidative stress is an important determinant in atherosclerosis development. Pain perception was associated with the activation of the anterior insular cortex and with the functional connectivity from the anterior insular cortex to the primary somatosensory cortex during painful stimulation.

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The possibility to readjust the length intraoperatively was seen as a good feature. A sample of 58 people with recent traumatic SCI was followed up at 12 months post-discharge from inpatient rehabilitation. To date, no evidence of linkage or association has been reported for this gene in humans with oral clefts.

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In this paper, we discuss the use of three-dimensional microstructured substrates such as silicon dioxide micropillars, to interface with living cells. In 3 experiments, observers watched a model respond to a 6-item unique sequence in a serial reaction time task.

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Membrane hydraulic permeability changes during cooling of mammalian cells. To assess utility of a national patient register to compare outcomes of infants in our unit before and after November 1st 2008 as well as to hospitals that did not utilize n-BiPAP during the observation period. Morphology and Carrier Extraction Study of Organic-Inorganic Metal Halide Perovskite by One- and Two-Photon Fluorescence Microscopy. Through a critical use of the category academic void can be shown and alternative explanatory models can be offered.

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These include the LD50 test, the Up-and-Down Procedure and the Fixed Dose Procedure, which are regarded as having notable scientific deficiencies and low transferability to humans. The Extended Glasgow Outcome Scale (GOS-E), 3-level European Quality of Life 5 Dimension measure (EQ-5D-3L), and RTW status 12 months following surgical ATR repair were collected through structured telephone interviews conducted by trained interviewers. Mutation analysis of the CYP21A2 gene in congenital adrenal hyperplasia. Here, we show maternal cells that establish microchimerism in female offspring during development promote systemic accumulation of immune suppressive regulatory T cells (Tregs) with NIMA specificity. We determined the incidence, severity and risk factors of AG-associated AKI and assessed for associations with longer hospitalization and higher costs.

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Emerging roles of nucleolar and ribosomal proteins in cancer, development, and aging. We describe a case of MAS developing in a pregnant patient with SLE, who presented with fever and pancytopenia. This process of scaling the microfluidic architecture and utilizing autologous cells to line the channels and mitigate coagulation represents a promising avenue for therapy for patients suffering from a range of acute and chronic lung diseases.

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Novel illudalane sesquiterpenes from Encephalartos villosus Lehm. The study included 153 patients undergoing 171 elective lower extremity bypass procedures with single-piece autologous great saphenous vein from June 1, 2001, to December 31, 2014.

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A case-control study was done on 940 patients with incident breast cancer and 1,547 healthy female controls. In many catabolic diseases, such as sepsis, starvation, and cancer cachexia, endogenous glucocorticoids are elevated contributing to the loss of muscle mass and function. SEM confirmed the cytotoxicity of amitriptyline, whilst AAH revealed no significant changes in cytokine expression following amitriptyline, carbamazepine or gabapentin exposure compared with control. To perform a systematic review to analyze the association between occupational exposure to wood dust and cancer. Wollastonite-based bioceramic powders were synthesized by solid-state reaction between calcite and silica powder.

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General continuum approach for dissipative systems of repulsive particles. Strategic planning in population health and public health practice often uses single indicators of success or, when using multiple indicators, provides no mechanism for coherently combining the assessments. Recombinant diabody-based immunocapture enzyme-linked immunosorbent assay for quantification of rabies virus glycoprotein. Monitoring rapid endocytosis in the electron microscope via photoconversion of vesicles fluorescently labeled with FM1-43. With improved funding opportunities and research environment in neuroscience, vision research at several research institutes within the academy has made significant progress not only in the quantity of publications, but also in the quality of the work.

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However, in many practices, the emphasis of the type I error rate control often leads to a choice of a statistically valid multiple test procedure but the common sense is overlooked. The effectiveness of a novel neuromuscular electrostimulation method versus intermittent pneumatic compression in enhancing lower limb blood flow.

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Subsequent optimisation of both inhibitory activity and metabolic stability led to a novel series of meta-substituted 4-benzyl-2H-phthalazin-1-ones with low nanomolar, cellular activity as PARP-1 inhibitors and promising metabolic stability in vitro. Eligible patients included those receiving curative radiotherapy (RT) for head-and-neck cancer.

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The incidences of underlying disease, such as hypertension and heart disease, and the rate of antiplatelet agents use were significantly higher in the elderly group. Electron microscopy of solubilized Acholeplasma laidlawii membrane proteins reaggregated with Mycoplasma pneumoniae glycolipids. Biological therapy was suspended for at least 2 weeks in all patients, and was restarted without reactivation of arthritis.

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Propensity score matching algorithm was used to balance differences in baseline characteristics among MIS and O-LR groups. Main outcome measures included visual analog scale (VAS), endoscopic Lind-Kennedy scores, nasal resistence, pulmonary function in patientsone week before and after surgery, three months and six months after surgery. Our study showed lower PTI and FTI for the both feet big toes in the female joggers group.

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Both FDG-PET/CT and contrast-enhanced multidetector CT had very high sensitivity and specificity for the detection of recurrent ovarian cancer. Tuberculosis (TB) is one of the most serious health problems in Myanmar.

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Effects of platelet-rich fibrin and piezosurgery on impacted mandibular third molar surgery outcomes. Enzyme-coupled nanoplasmonic biosensing of cancer markers in human serum. Moreover, a higher activity of alkaline phosphatase was found for cells seeded under dynamic conditions. Systolic left ventricular function is preserved during therapeutic hypothermia, also during increases in heart rate with impaired diastolic filling.

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However, this procedure has several disadvantages, such as extra-drainage and self-tube removal. This paper discusses this, with particular reference to null hypothesis significance testing and the associated p-value. Cancer occurrence in ductal cells that normally lack ER would be unrelated to estrogen exposure or SERMs protection.

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Middle East aircrew use of alcohol, tobacco, coffee, and medicaments. The presentation of the 12-year-old patient was reduction in urine output along with joint pains, seemed like that of diabetes mellitus, as he was already on insulin.

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Homeodomain binding motifs modulate the probability of odorant receptor gene choice in transgenic mice. Showing the specific activation of TLR4 and the secretion of one major functional chemokine-CXCL1, the homolog of human IL-8-, we elucidate a new mechanism in which Hepatic Stellate Cells play a central role in the recognition of gut microbes by the liver at steady state. This account summarizes the newest naphthylmethyl (NAP) ether-mediated IAD as well as all the types of mediations for stereospecific construction of various 1,2-cis linkages, not only for beta-mannopyranoside, but also for other linkages almost without exception, including beta-L-rhamnoside. No association of the polymorphisms from IL6 and IL6R genes with schizophrenia was found.

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IVC stenting was performed using a stent loaded with (125)I seeds strands (the irradiation stent) in 33 patients (Group A) and 28 patients with a bare stent (Group B). The use of preclinical models is a key component of translational research in oncology. On and off retinal cells in parallel channel neural communication. X-ray diffraction (XRD) and corresponding selected area electron diffraction (SAED) patterns demonstrate the SnS(2) nanowire is hexagonal polycrystalline.

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Whereas some studies reported smaller hippocampal volumes, little evidence was found for abnormal amygdala volumes. The addition of a concurrent task did not differentially affect walking outcomes in people with and without transfemoral amputation.

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Our sonographic examination suggested a right orbital hypoplasia and a hemiatrophy of the nose. However, high-throughput technologies reflect biological fluctuations and methodological errors. Addition of alfentanil to propofol target-controlled infusion did not confer cardiovascular benefits and, at the higher concentration, alfentanil increased the incidence of hypoxaemia. Early rheumatoid arthritis patients using combination therapy improved both disease activity and PA, a beneficial effect persisting for at least 1 year. Results are novel in showing the rate of decline in running biomechanics on a per-year basis and that mechanical reductions at the ankle but not at the hip or knee were correlated with age, confirming a previous observation of biomechanical plasticity with age showing reduced ankle but not hip function in gait.

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Using these models, we evaluated the detailed reaction process, including energies and geometric structures of intermediates and transition states under the influence of different solvation models and electrode potentials. Study on activity of antistaphylococcal antibiotic batumin against methicillin resistant strains of staphylococci Physiologic VD/VT, alveolar VD/VT, and AVDSF were calculated with each arterial blood gas using capnography data. The program can be used in multiple applications including the determination of cochlear dimensions, especially its length, and post-operative positions of cochlear implant (CI) electrode carriers. Predicting substance use in emerging adulthood: A genetically informed study of developmental transactions between impulsivity and family conflict.

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Although many mutations in RUNX2/CBFA1, an osteoblast-specific transcription factor, have been identified as causes of CCD, it is unclear whether these mutation genotypes relate to various symptoms. Sixty single rooted human premolar teeth were divided into 3 Groups of 20 teeth each Group I (20 Teeth): prepared using hand K Files, Group II (20 Teeth): prepared using ProTaper rotary system and Group III (20 Teeth): prepared using Mtwo rotary system.

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To show how they might interact, the effects of NPY on plasma insulin and on 5-HT metabolism in the paraventricular hypothalamic nucleus (PVN), the ventromedial hypothalamic nucleus (VMN), the arcuate nucleus (ARC), and the locus coeruleus (LC) were measured in separate groups of intact, adrenalectomized (ADX), or ADX and CORT replaced Sprague-Dawley rats. It appeared that the plaques formed by insertion of collapsed vesicles into membranes and/or that collapsed vesicles formed by pinching off of plaques. Study results on quality of life (QoL) between patients receiving an anterior resection (AR) or abdominoperineal resection (APR) for rectal cancer vary greatly. Antisera to adenovirus 18 or mycoplasma orale did not react with the exfoliated cells.

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Whether women are more susceptible to lung cancer than men has been controversial. Pre-epidemic rudbeckia samples clustered separately from modern strains.

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Ticks are distributed worldwide and affect human and animal health by transmitting diverse infectious agents. Pharmacological analysis of the function and receptor structure of the pain-sensitive nerve endings

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Using a standard phosphoprotein alpha-casein as a model system, we demonstrate that this OTC-IMAC method can detect a number of phosphopeptides after in-gel digestion with mid-fmol protein sample loading. Such a construction of the channel allows one to reduce the aspect ratio (the ratio of the channel breadth b to its thickness w) without increasing the zone broadening. Investigation using this in vitro paradigm revealed frequency-dependent modulation upon the excitability and functional connectivity of cerebellar slices.