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Topiramate is a unique antiseizure medication that is used in treatment of partial and generalized seizures. Topiramate has been rarely associated with hepatic injury and largely when used in combination with other anticonvulsant medications. Topiramate is also used with other medications to control seizures in people who have Lennox-Gastaut syndrome (a disorder that causes seizures and developmental delays). Topiramate is also used to prevent migraine headaches but not to relieve the pain of migraine headaches when they occur.

Other names for this medication:
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Topiramate is used alone or with other medications to treat certain types of seizures including primary generalized tonic-clonic seizures (formerly known as a grand mal seizure; seizure that involves the entire body) and partial onset seizures (seizures that involve only one part of the brain). Topiramate is also used with other medications to control seizures in people who have Lennox-Gastaut syndrome (a disorder that causes seizures and developmental delays). Topiramate is also used to prevent migraine headaches but not to relieve the pain of migraine headaches when they occur. Topiramate is in a class of medications called anticonvulsants. It works by decreasing abnormal excitement in the brain.

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The SDF-1-mediated cell proliferation was analyzed by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay. Influence of physical training, aortic constriction and exogenous anterior pituitary hormones on the heart weights of hypophysectomized rats. All experts agreed on the proposed adaptations of the GMFM-88 for children with CP and CVI. Moreover, immunohistochemical analysis revealed evidence of inflammation and anti-apoptotic action of DOX by deregulation of various biomarkers. Urine testing to monitor the impact of HPV vaccination in Bhutan and Rwanda.

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Overall, efficacious induction of G0/G1 cell cycle arrest at low concentrations, and induction of apoptosis at higher concentrations are interesting 4HWE-mediated phenomena that are accompanied by a complex array of molecular events. Examinations were performed on admission (day 1) and during follow-up (days 3, 10 and 21) and included a questionnaire regarding the presence of blurred vision, standardized refraction measurements and optical coherence tomography. To elucidate the pharmacokinetic/pharmacodynamic (PK/PD) index that predicts colistin efficacy against Acinetobacter baumannii in neutropenic murine thigh and lung infection models, and to determine the extent of the emergence of resistance in vivo to colistin.

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Capillary ultrastructure and mitochondrial volume density in skeletal muscle in relation to reduced exercise capacity of patients with intermittent claudication. Calculation of etonogestrel and ethinylestradiol interaction/control ratios confirmed the absence of pharmacokinetic interactions.

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We report the case of a 30-year-old woman with a three-year history of papules, nodules, and multiple ulcers of the left lower extremity. The objective of the study was the assessment of the GIP effect on the expression and secretion of CGRP-I and Pro-CT in human adipocytes, CGRP-I and CT gene expression in adipose tissue (AT) from obese vs.

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Compared with subjects with normal blood pressure patients with hypertension had greater myocardial mass, higher frequency of left ventricular hypertrophy with cases of concentric hypertrophy and isolated hypertrophy of interventricular septum. Relationship between anti-double-stranded DNA antibodies and exacerbation of renal disease in patients with systemic lupus erythematosus. Youth with a family history of substance abuse have disrupted white matter microstructure, which likely contributes to less efficient cortical processing and may act as an intrinsic risk factor contributing to an increased susceptibility of developing AUD. By viewing the phase as the argument of a vector we find out that CCD sampling introduces errors into the measurement and the phase is nonlinear to the equivalent wavelength at the abrupt discontinuities. Using the same paradigm, we tested the efficiency of linguistic cues with various hierarchical categorization principles in regional structuring.

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Daily positive affect buffered the immediate and longer-lasting negative impact of stress on days of low to moderate levels of stress. Furthermore, recent studies suggest that the UPR is induced in osteoclast precursors after RANKL stimulation and has roles in osteoclastogenesis. To investigate the possibility that the level of Tie2 mRNA in peripheral blood could reflect the severity of sepsis.

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The study group was composed of 12 patients managed with double nerve transfer whereas the 8 patients in the grafted group constituted the control group. The aim of this study was to identify the aspects of cardiac physiology associated with depressive disorder early in life by examining measures of autonomic cardiac control in a community-based sample of depressed adolescents at an early phase of illness, and matched on a number of demographic factors with a nondepressed comparison group. Living donor liver transplantation in a recipient with anti-Fy(a) and Jk(a) antibodies.

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Glioblastoma (GBM) is the most devastating tumor of the brain, characterized by an almost inevitable tendency to recur after intensive treatments and a fatal prognosis. In this article, the detection of phase singularities based on the branch point potential (BPP) method is investigated. We observed meaningful improvement in the performance of the new standard as well as time savings for clinical providers with each room entry. We report significant advances in the fabrication of low loss chalcogenide microstructured optical fiber (MOF). The use of computer-assisted surgery in fresh extraction sites is a procedure that has not been evaluated because of technical difficulties: teeth extraction eliminates references for surgical guides.

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Distribution of nucleic acids in the crystalline lens of the bovines Contribution on the differential diagnosis of multiple valve defects by means of ultrasonic cardiography. What Makes Hydroxamate a Promising Anchoring Group in Dye-Sensitized Solar Cells?

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Finding the Truth in Medical Imaging: Painting the Picture of Appropriateness for Magnetic Resonance Imaging in Canada. Tea is one of the most common and popular beverages spanning vast array of cultures all over the world.

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Using a discovery and validation approach, we identified a pharmacogenetic predictive model for neutropenia. The IC(50) values for miR-21-silencing cells and control cells were 28.31 and 35.89 nmol/L, respectively. The epidermal melanocytes were positive for S-100, Melan-A and HMB-45, but the dermal nests of melanocytes were negative for HMB-45 and positive for S-100 and Melan-A. Percutaneous repair of a nonunion pubic ramus fracture using a metallic stent scaffold and cement osteoplasty.

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This article examines the perceived benefits of graduate-only pre-registration programmes in mental health nursing, and the potential social aspiration and attrition problems that may result. The obtained two-dimensional composite grain membranes exhibit superparamagnetic behavior at room temperature but responds astutely to an external magnetic field. Treatment included administration of acepromazine (0.25 mg, IM, or 2.5 mg, PO, q 8 h), buprenorphine (0.075 mg, PO, q 8 h), and medetomidine (0.1 mg, IM, q 24 h) and decompressive cystocentesis and SC administration of fluids as needed. A pilot study of antipsychotic prescribing decisions for acutely-Ill hospitalized patients. HPV-OPSCC is commonly diagnosed by RT-qPCR of HPV-16 E6 and E7 oncoproteins or by cyclin-dependent kinase inhibitor 2A, multiple tumor suppressor 1 (p16) immunohistochemistry (IHC).

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Arthroscopic management of massive rotator cuff tears: an evaluation of debridement, complete, and partial repair with and without force couple restoration. In this study, we sought to determine the role of beta-catenin in head and neck carcinogenesis. This pilot study aimed to investigate baseline quality of life, anxiety, and depression scores in women attending a multidisciplinary vulvar clinic and to simon kovar 24 daily exercises for kids assess whether attendance was associated with improvement in quality of life and psychological symptoms. Conformal radiotherapy in the treatment of advanced juvenile nasopharyngeal angiofibroma with intracranial extension: an institutional experience. No observations have been made, however, demonstrating direct chemokine-mediated promotion of host defense in vivo.

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Bimodal endoscopic probe combining white-light microscopy and optical coherence tomography. Performing myomectomy increases the need for transfusion (Grade 2) without an increase in the risk of hysterectomy (Grade 3) and other life-threatening complications (Grade 4-5). Today, ketoconazole shampoo pediatric occupational therapy SBT is a common curriculum component in surgical education that can significantly complement clinical learning, performance, and patient care experiences. The fabrication of polyelectrolyte multilayer capsules with controllable submicron-sized subdomains and the in situ synthesis of silver nanoparticles are reported.

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